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| Date | Opponents | Time | At | HRs |
| Aug. 1 | at Toronto | L 5-8 | Borcowski(L,0-2)-Kida-Nitcowski-Brocail-Jones | To Clark(18),K Garcia(7),Ausmus(8) |
| Aug. 2 | Chi.White Sox | L 2-6 | Moehler(L,8-11)-N Cruz-Blair-Nitcowski-F Cordero | Encarnacion(12)|
| Aug. 3 | Chi.White Sox | L 6-9 | Thompson(L,9-10)-Kida-Blair-Jones | Alvarez(2),Palmer(26) |
| Aug. 5 | at Baltimore | L 3-6 | Weaver(L,6-8)-Blair | Encarnacion(13) |
| Aug. 6 | at Baltimore | W 4-3 | Mlicki(W,6-10)-Jones(S,16) | Catalanotto(9),Encarnacion(14) |
| Aug. 7 | at Baltimore | L 4-5 | Borcowski(L,0-3)-Cordero-Brocail | Palmer(27) |
| Aug. 8 | at Baltimore | W 5-2 (11) | Moehler-Brocail(W,4-3)-Jones(S,17) | D.Cruz(7) |
| Aug. 10 | at Texas | L 3-4 (12) | Thompson-Cordero-Nitcowski-Brocail-N.Cruz(L,2-4) | |
| Aug. 11 | at Texas | L 2-8 | Blair(L,1-9)-N.Cruz-Nitcowski-Kida | Easley(13),Encarnacion(15) |
| Aug. 12 | at Texas | W 3-1 | Mlicki(W,7-10)-Cordero-Brocail-Jones(S,18) | To Clark(19) |
| Aug. 13 | Anaheim | W 8-7 | Borcowski-Kida-Nitcowski-Cordero-Brocail-Jones | Catalotto(10),Palmer(28),To Clark(20) |
| Aug. 14 | Anaheim | L 4-7 | Moehler(L,8-12)-Nitcowski-N.Cruz | To Clark(21) |
| Aug. 15 | Anaheim | L 2-10 | Thompson(L,9-11)-Blair | |
| Aug. 16 | Tampa Bay | L 1-9 | Weaver(L,6-9)-N.Cruz-Brocail | |
| Aug. 17 | Tampa Bay | W 3-1 | Mlicki(W,8-10)-Brocail-Jones(S,19) | Palmer(29) |
| Aug. 18 | Tampa Bay | L 0-4 | Borkowski(L,1-4)-Nitcowski-Anderson-Kida | |
| Aug. 20 | at Anaheim | L 1-5 | Moehler(L,8-13)-Nitcowski-Cordero-Blair | Easley(14) |
| Aug. 21 | at Anaheim | W 5-0 | Weaver(W,7-9)-Brocail-Jones | |
| Aug. 22 | at Anaheim | W 12-3 | Mlicki(W,9-10)-Cordero-Brocail-Anderson | Encarnacion(16) |
| Aug. 23 | at Anaheim | L 5-6 | Borcowski-Nitcowski-Kida-Cordero-Brocail(L,4-4) | K.Garcia(8) |
| Aug. 24 | at Seattle | L 0-5 | Blair(L,1-10)-Nitcowski | |
| Aug. 25 | at Seattle | L 2-3 | Moehler(L,8-14)-Cordero | To Clark(22) |
| Aug. 27 | Baltimore | W 5-4 | Weaver(W,8-9)-Jones(S,20) | Kapler(14),Easley(15) |
| Aug. 28 | Baltimore | W 4-3 | Mlicki(W,10-10)-Cordero-Brocail-Jones(S,21) | Easley(16) |
| Aug. 29 | Baltimore | L 4-11 | Nitcowski(L,2-4)-Kida-Anderson-N.Cruz-Blair | To Clark(23),Easley(17,18) |
| Aug. 30 | Texas | W 1-0 | Moehler(W,9-14) | Kapler(15) |
| Aug. 31 | Texas | W 14-6 | Borcowski-Blair-Cordero(W,1-0)-Anderson | |