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| Date | Opponent | Time | Pitchers | HRs |
| Jun. 1 | Cleveland | L 0-2 | Florie(L,3-1)-Crow-Runyan-Brocail | |
| Jun. 2 | Cleveland | L 2-8 | Thompson(L,3-6)-Worrell-T Jones-Runyan | To Clark(8) |
| Jun. 3 | at Toronto | L 1-5 | Greisinger(L,0-1)-Runyan-Crow | |
| Jun. 4 | at Toronto | L 6-8 | Moehler(L,5-5)-Sager-Runyan-Brocail | To Clark(9),Easley(17) |
| *****Interleague***** | ||||
| Jun. 5 | at Milwaukee | L 3-7 | Castillo(L,2-4)-Worrell-Runyan-Crow | Higginson(10) |
| Jun. 6 | at Milwaukee | W 9-3 | Florie(W,4-1)-Sager | To Clark(10) |
| Jun. 7 | at Milwaukee | W 4-1 | Thompson(W,4-6) | To Clark(11),Higginson(11) |
| Jun. 8 | Houston | L 5-9 | Greisinger-Brocail-T Jones(L,0-2)-Runyan | |
| Jun. 9 | Houston | L 3-5 | Moehler-T Jones(L,0-3)-Brocail | |
| Jun. 10 | Houston | L 3-10 | Castillo(L,2-5)-Sager-Bochtler-Crow-Worrell-T Jones | Oliver(4) |
| *****Interleague***** | ||||
| Jun. 12 | at Kansas City | L 3-7 | Florie(L,4-2)-Bochtler-Castillo | Randa(3),To Clark(12) |
| Jun. 13 | at Kansas City | W 7-1 | Thompson(W,5-6) | Higginson(12),Randa(4) |
| Jun. 14 | at Kansas City | L 0-2 | Greisinger(L,0-2)-Runyan-Brocail | |
| Jun. 15 | Minnesota | W 3-2 | Moehler(W,6-5)-Brocail-T Jones(S,10) | Higginson(13) |
| Jun. 16 | Minnesota | L 5-8 | Harriger(L,0-1)-Runyan-Worrell-Crow | Bartee(3) |
| Jun. 17 | Minnesota | W 6-2 | Florie(W,5-2)-Runyan-Brocail | To Clark(13,14) |
| Jun. 18 | Kansas City | L 3-5 | Thompson(L,5-7)-Bochtler-Crow-Runyan | |
| Jun. 19 | Kansas City | L 4-8 | Greisinger(L,0-3)-Castillo | |
| Jun. 20 | Kansas City | W 4-3 | Moehler(W,7-5)-Runyan-Brocail-T Jones(S,11) | Gonzalez(6),Higginson(14) |
| Jun. 21 | Kansas City | L 5-6 | Harriger(L,0-2)-Worrell-Runyan | Gonzalez(7),To Clark(15) |
| *****Interleague***** | ||||
| Jun. 22 | at St.Louis | L 1-4 | Florie(L,5-3)-Bochtler-Runyan-Crow | Bako(2) |
| Jun. 23 | at St.Louis | W 8-1 | Thompson(W,6-7)-Brocail-T Jones | To Clark(16),Alvarez(1,2) |
| Jun. 24 | Chi. Cubs | W 7-6 (11) | Greisinger-Runyan-Crow-Brocail(W,3-0) | Gonzalez(8),Higginson(15) |
| Jun. 25 | Chi. Cubs | W 6-4 | Moehler-Runyan-Anderson--T Jones | Easley(18),To Clark(17) |
| Jun. 26 | Cincinnati | L 3-4 | Castillo-Bochtler-Brocail(L,3-1)-Crow | Cruz(2) |
| Jun. 27 | Cincinnati | L 5-6 (13) | Powell-Runyan-Anderson-T Jones-Crow-Harriger(L,0-3) | Alvarez(3) |
| Jun. 28 | Cincinnati | L 2-5 | Thompson(L,6-8)-Bochtler-Harriger | Easley(19),Higginson(16) |
| Jun. 30 | at Pittsburgh | W 3-0 | Moehler(W,8-5) | |