| Date | Opponent | Time | Pitchers | HRs |
| Mar. 31 | at Tampa Bay | W 11-6 | Thompson(W,1-0)-Runyan-Duran-Florie-Bochtler | L Gonzalez(1) |
| Apr. 1 | at Tampa Bay | L 8-11 | Moehler(L,0-1)-Sager-Runyan-Florie-Brocail-Duran | |
| Apr. 2 | at Tampa Bay | L 1-7 | Worrell(L,0-1)-Runyan-Bochtler-Brocail-T Jones | B L Hunter(1) |
| Apr. 3 | at Baltimore | L 2-10 | Sanders(L,0-1)-Florie-Duran | |
| Apr. 4 | at Baltimore | L 1-2 | Keagle(L,0-1)-Runyan-Bochtler-Brocail | Easley(1) |
| Apr. 5 | at Baltimore | L 3-6 | Thompson(L,1-1)-Sager-Runyan-T Jones | |
| Apr. 7 | Tampa Bay | W 3-1 | Moehler-Runyan-Florie(W,1-0)-Brocail-T Jones(S,1) | |
| Apr. 9 | Tampa Bay | PPD(Postponed) by Rain |
| Apr. 10 | Baltimore | W 7-1 | Worrell(W,1-1)-Runyan-T Jones | BL Hunter(2);Higginson(1);Easley(2) |
| Apr. 11 | Baltimore | L 0-2 | Thompson(L,1-2)-Runyan-Bochtler | |
| Apr. 12 | Baltimore | L 3-6 | Keagle(L,0-2)-Sager-Runyan-Florie-Duran | |
| Apr. 13 | at Texas | L 1-10 | Moehler(L,0-2)-Duran-Bochtler-Brocail-Florie | |
| Apr. 14 | at Texas | L 2-11 | Sanders(L,0-2)-Bochtler-T Jones | |
| Apr. 15 | at Texas | L 3-7 | Worrell(L,1-2)-Runyan-Florie-Brocail | |
| Apr. 17 | N.Y. Yankees | L 2-11 | Thompson(L,1-3)-Bochtler-Duran-Brocail-T Jones | |
| Apr. 18 | N.Y. Yankees | L 3-8 | Keagle(L,0-3)-Sager-Runyan-Florie-Brocail-Sanders | |
| Apr. 19 | N.Y. Yankees | W 2-1 | Moehler(W,1-2)-T Jones(S,2) | |
| Apr. 21 | Boston | L 4-11 | Worrell(L,1-3)-Sager-Duran-Brocail-Runyan | Easley(4);Bartee(1);L Gonzalez(2);To Clark(2) |
| Apr. 22 | Boston | L 5-8 | Thompson-Florie-Brocail-Runyan-T Jones(L,0-1)-Duran | Easley(5) |
| Apr. 24 | at N.Y. Yankees | L 4-8 | Keagle(L,0-4)-Duran-Bochtler-Runyan | |
| Apr. 25 | at N.Y. Yankees | L 4-5 | Moehler-Sager-Runyan(L,0-1)-Florie | |
| Apr. 26 | at N.Y. Yankees | PPD(Postponed) by Rain |
| Apr. 27 | at Boston | L 5-6 | Thompson-Brocail-Runyan(L,0-2)-Florie | |
| Apr. 28 | at Boston | W 7-5 | Castillo-Florie(W,2-0)-T Jones(S,3) | Higginson(2),BL Hunter(3) |
| Apr. 29 | Texas | L 1-4 | Keagle(L,0-5)-Runyan-Brocail | Oliver(1) |
| Apr. 30 | Texas | W 7-2 | Moehler(W,2-2) | Easley(6) |
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